Health professions education must move beyond knowledge and skills-based domains to address student agency in diversity, equity, and inclusion.When DEI is addressed in health occupation courses, students have increased ability to maintain cultural competency, contribute to health disparity reduction, and foster a diverse health professions workforc
Considering the involvement of oxidative stress in the etiology of many non-communicable diseases, food-derived antioxidant peptides (FDAPs) are strong candidates for nutraceutical development for disease prevention and management.This paper reviews current evidence on the transepithelial transport and cellular mechanisms of antioxidant activities
Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in maladaptive renal repair in mice and humans.Using single-cell transcriptomic and mouse genetic approaches, we show that proximal tubular (PT) cells Spanners develop a molecularly distinct, pro-inflamma
Abstract Small ruminants are suited to a wide variety of habitats and thus represent promising study models for identifying genes underlying adaptations.Here, we considered local Mediterranean breeds of goats (n = 17) and sheep (n = 25) from Italy, France and Spain.Based on historical archives, we selected the breeds potentially most linked to a te
The NRF2 pathway is a metabolic- and redox-sensitive signaling axis in which the transcription factor controls the expression of a multitude of genes that enable cells to survive environmental stressors, Collections such as oxidative stress, mainly by inducing the expression of cytoprotective genes.Basal NRF2 levels are maintained under normal phys